Originally Vanguard was a task force put together by the Central Intelligence Agency and placed under the command of Agent Brian Grace. It's sole purpose was to keep an eye on all super powered individuals and arrest any that posed a threat to the United States. However, the task force was too small for such a mission and so it eventually became a branch of the U.S. Government all its own. Vanguard now has hundreds upon hundreds of agents, both normal and "enhanced." They are the greatest police force the United States has and they outrank all other government agencies. Vanguard is now under the command of the ruthlessly intelligent Jackson Cole. Under his leadership Vanguard and the United States have made steps to recognize certain groups as "Official" super groups. Two such teams are the Avengers and the Fantastic Five. Vanguard has also created a super team of its own, the Thunderbolts, which answers to the Director of Operations, the Deputy Director, and the U.S. Government.
- Brian Grace (Director)
- Victor Mortel (Deputy Director)
- Jessica Hill (Liaison to the Avengers & Fantastic Five)